Latest news and research outcomes

The APOE (apolipoprotein E) gene is involved in making certain proteins. People who carry APOE4, a version of the gene, have an increased genetic risk of developing Alzheimer’s disease. Knowing whether someone carries APOE4 helps scientists look for early brain...

The hallmark of Alzheimer's disease is development of plaques and tangles of certain proteins in the brain. The plaques, sometimes called clumps, are made up of a form of protein called amyloid. The tangles are due to clustering of a protein called tau within the...

No. The onset of dementia usually occurs after the age of 65. However, about 5% of people with Alzheimer’s disease will develop symptoms before the age of 65 - sometimes in their 30’s and 40’s.

No. Dementia is a general term relating to a loss of cognitive function. There are several types of dementia, which are caused by different underlying changes in the brain. The most common form is Alzheimer’s, accounting for about two thirds of dementia cases. Other...

Most dementia research studies are looking for particular people. Often this can be based on the severity of someone’s dementia. To help ensure you are matched to the right studies, you are asked to describe your symptoms or the volunteer’s symptoms selecting from...

StepUp for Dementia Research asks about symptoms and a few medical conditions and tests which may be unfamiliar to you. You do not need to answer these questions, but providing this information may help match you to studies. The information provided here may help you.

You can update your information at any time. You can log in and provide your unique username and password through the website, or call the helpdesk to change your details. If you have registered on the telephone or via post, you will be asked some personal information...

When you first register you will be asked a few simple questions about yourself or the person you are registering. This includes address, date of birth, details of any diagnosis and brief details of any past major health issues. Once you have registered, you can...

Yes, you can register on behalf of one or more persons providing that (1) to the best of your knowledge, the person you have registered has not expressed any reluctance to participate in StepUp for Dementia Research and (2) it is your opinion that registration is in...

If you register online, you nominate an email address as your username and then create a password. If you forget your password it can be reset using the ‘forgotten password’ link or by calling the helpdesk for assistance. Passwords can only be changed once every 24...